Associate Professor, IIT Bhubaneshwar

Dr. Anasuya Roychowdhury

Department : Basic Sciences

Publications

1ATAD2 Suppression Enhances the Combinatorial Effect of Gemcitabine and Radiation in Pancreatic Cancer Cells, M. Dutta, D. Mohapatra, A.P. Mohapatra, S. Senapati, A. Roychowdhury. Biochem Biophys Res Commun. 2022 Oct 15 ; 635:179-186. doi: 10.1016/j.bbrc.2022.10.021 [I.F=3.575].
2MicroRNA-217 Modulates Pancreatic Cancer Progression via Targeting ATAD2. M. Dutta, B. Das, D. Mohapatra, P Behera, S Senapati, A. Roychowdhury, Life Sci. 2022 Jul 15;301:120592. doi: 10.1016/j.lfs.2022.120592. [I.F=5.037].
3Effects of Probiotics at the Interface of Metabolism and Immunity to Prevent Colorectal Cancer-Related Gut-inflammation: A Systematic Network and Meta-analysis with Molecular Docking Studies, S. Patra, N. Sahu, S. Saxena, B. Pradhan, S. K. Nayak, A. Roychowdhury, Front Microbiol. 2022 May 27;13:878297. doi: 10.3389/fmicb.2022.878297 [I.F=5.64].
4Emerging oncogene ATAD2: Signaling cascades and therapeutic initiatives. A Nayak, M Dutta, A Roychowdhury, Life Sci. 2021 Jul 1;276:119322. doi: 10.1016/j.lfs.2021.119322 [I.F=5.037].
5Systematic network and meta-analysis on the antiviral mechanisms of probiotics: a preventive and treatment strategy to mitigate SARS-CoV-2 infection. S Patra, S Saxena, N Sahu, B Pradhan, A Roychowdhury, Probiotics and antimicrobial proteins, 2021 Aug;13(4):1138-1156. doi: 10.1007/s12602-021-09748-w [I.F=4.609].
6Oncogenic potential of ATAD2 in stomach cancer and insights into the protein-protein interactions at its AAA+ ATPase domain and bromodomain. A Nayak, S Kumar, SP Singh, A Bhattacharyya, A Dixit, A Roychowdhury. J Biomol Struct Dyn. 2021 Jan 13:1-17. doi: 10.1080/07391102.2021.1871959 [I.F=3.392].
7HIF1α-dependent upregulation of ATAD2 promotes proliferation and migration of stomach cancer cells in response to hypoxia. A Nayak, AD Roy, N Rout, SP Singh, A Bhattacharyya, A Roychowdhury, Biochem Biophys Res Commun. 2020 Mar 19;523(4):916-923. doi: 10.1016/j.bbrc.2019.12.130 [I.F=3.575].
8Mechanisms of interactions of the nucleotide cofactor with the RepA protein of plasmid RSF1010. Binding dynamics studied using the fluorescence stopped-flow method IE Andreeva, A Roychowdhury, MR Szymanski, MJ Jezewska, W. Bujalowski. Biochemistry. 2009 Nov 10; 48(44):10620-36. doi: 10.1021/bi900940q [I.F=3.162].
9Interactions of the Escherichia coli DnaB−DnaC Protein Complex with Nucleotide Cofactors. 1. Allosteric Conformational Transitions of the Complex. A Roychowdhury, MR Szymanski, MJ Jezewska, W Bujalowski, Biochemistry. 2009 Jul 28;48(29):6712-29. doi: 10.1021/bi900050x [I.F=3.162].
10Mechanism of NTP Hydrolysis by the Escherichia coli Primary Replicative Helicase DnaB Protein. 2. Nucleotide and Nucleic Acid Specificities. A Roychowdhury, MR Szymanski, MJ Jezewska, W Bujalowski. Biochemistry. 2009 Jul 28; 48(29):6730-46. doi: 10.1021/bi9000529 [I.F=3.162].
11Escherichia coli DnaB Helicase−DnaC Protein Complex: Allosteric Effects of the Nucleotides on the Nucleic Acid Binding and the Kinetic Mechanism of NTP hydrolysis. 3. A Roychowdhury, MR Szymanski, MJ Jezewska, W Bujalowski. Biochemistry. 2009 Jul 28; 48(29):6747-63. doi: 10.1021/bi9000535 [I.F=3.162].
12Accumulation of p-hydroxybenzoic acid in hairy roots of Daucus carota. D Sircar, A Roychowdhury, A Mitra J Plant Physiol. 2007 Oct; 164(10):1358-66. doi: 10.1016/j.jplph.2006.08.002 [I.F=3.549].
13Kinetic mechanisms of the nucleotide cofactor binding to the strong and weak nucleotide-binding site of the Escherichia coli PriA helicase. 2 AL Lucius, MJ Jezewska, A Roychowdhury, W Bujalowski. Biochemistry. 2006 Jun 13; 45(23):7217-36. doi: 10.1021/bi051827e [I.F=3.162].
1Patra S. and Roychowdhury A., Lactobacillus plantarum shows Probiotic Potential and Antioxidant properties for the Prevention of Colorectal Cancer. J. Biol. Chem. (2023) 299(3S) S53-54, https://doi.org/10.1016/j.jbc.2023.103169.
2Roychowdhury A, Nayak A, Kumar S, Dixit A, BhattacharyyaA. Hypoxia-responsive and HIF1α-regulated AAA+ ATPase ATAD2 shows high oncogenic potential in stomach cancer [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2022; 2022 Apr 8-13. Philadelphia (PA): AACR; Cancer Res 2022;82(12_Suppl):Abstract nr 5680. https://doi.org/10.1158/1538-7445.AM2022-5680
3Nayak A, Kumar S, Bhattacharyya A, Dixit A, Roychowdhury A (2019). Cross-Cancer Study with a Special Emphasis on Stomach Cancer Reveals ATAD2 as Diagnostic and Prognostic Biomarker. Mol Biol Cell 30(26), pp. P-1150. https://doi.org/10.1091/mbc.E19-11-0617.
4Roychowdhury A, Nayak A, Bhattacharyya A. (2019). AAA+ ATPase ATAD2 signalling networks in gastric cancer. Biochem Mol Biol J Vol.5; doi: 10.21767/2471-8084-C3-029.
5Roychowdhury A, Robert J, Lee BH, Finley D. Characterization of the Non-catalytic Inhibitory Effect of Ubp6 on Proteasome Function. FASEB J. 27:553.23, 2013. https://doi.org/10.1096/fasebj.27.1_supplement.553.23
6Roychowdhury A, Jezewska MJ, Bujalowski W. Nucleotide Control of Replication Initiation: NTPase Mechanisms of E.coli DnaB-DnaC Complex. Biophysical J., vol. 96, issue 3, pp. 209a-209a, 2009.
7Roychowdhury A, Jezewska MJ, Bujalowski W. (2009). E.coli DnaB-DnaC Complex with Nucleotide Cofactors: An Allosteric Control of Recognition Process in DNA Replication. Special Issue: The 23rd Symposium of The Protein Society 2009: Abstract 235, Protein Science. vol. 18, issue S1, pp 137.
8Roychowdhury A, Jezewska MJ, Bujalowski W. (2008) Functional Studies of E.coli DnaB-DnaC Complex Indicates Its Role As a Part of Primosome. 2008 Biophysical Society Meeting Abstracts. Biophysical J., Supplement, vol. 94, issue 2, Abstract, pp. 675.
9Lucius, AL, Jezewska MJ, Roychowdhury A, Bujalowski W. (2006) Kinetic Mechanisms of the nucleotide Cofactor binding to the Strong and Weak Nucleotide-Binding Site of the Escherichia coli PriA Helicase. 2006 Biophysical Society Meeting Abstracts. Biophysical J., Supplement, vol. 90, Abstract, 981-Pos.
Dutta M, Patra S, Saxena S, Roychowdhury, A*. Antimicrobials: Targets, Functions and Resistance. An invited book chapter of “Biomolecular Engineering Solutions for Renewable Specialty Chemicals: Microorganisms, Products, and Processes” (John Wiley & Sons, Inc.); pages 77-109; October 25, 2021.