Associate Professor, IIT Gandhinagar

Sudipta Basu

Department : Chemistry

Research Interests

● Chemical biology of mitochondria and endoplasmic reticulum (ER)
● Development of self-assembled novel nano-scale materials
● Design and synthesis of small molecules for understanding cancer biology
● Organic synthesis
● Nanobiotechnology

Professional Summary

Associate Professor, Indian Institute of Technology Gandhinagar (July 2018 to Present)
DBT-Ramalingaswami Fellow, Indian Institute of Science Education and Research (IISER) Pune, (2012 to present)
Postdoctoral Fellow, Brigham and Women’s Hospital, Harvard Medical School, Boston, USA (Dec 2006 – Nov 2011)

Publications

1. S. Pandey, S. Patil, N. Ballav, S. Basu*, “Spatial targeting of Bcl-2 on endoplasmic reticulum and mitochondria in cancer cells by lipid nanoparticles”, J. Mater. Chem. B, 2020, 8, 4259-4266.
2. S. Patil, D. Ghosh, M. Radhakrishna, S. Basu*,”Mitochondrial Impairment by Cyanine-Based Small Molecules Induces Apoptosis in Cancer Cells”, ACS Med. Chem. Lett., 2020, 11, 23-28. (Highlighted as Cover Page).
3. A. Nandi, C. Ghosh, S. Basu*, “Polymer conjugated graphene-oxide nanoparticles impair nuclear DNA and Topoisomerase I in cancer”, Nanoscale Adv. 2019, 1, 4965-4971.
4. A. Nandi, C. Ghosh, A. Bajpai, S. Basu*, “Graphene oxide nanocell for impairing topoisomerase and DNA in cancer cells” J. Mater. Chem. B. 2019, 7, 4191-4197.
5. S. Patil, S. Pandey, A. Singh, M. Radhakrishna, S. Basu*, “Hydrazide–Hydrazone Small Molecules as AIEgens: Illuminating Mitochondria in Cancer Cells”, Chem. Euro. J. 2019, 25, 8229-8235. (Hot paper).
6. C. Ghosh, A. Nandi, S. Basu*, “Supramolecular self-assembly of triazine-based small molecule: targeting endoplasmic reticulum in cancer cells”, Nanoscale, 2019, 11, 3326-3335.